Forum for Iontophoresis Hyperhidrosis and excessive sweating

support · Site Admin Joined: 20 Mar 2008 Posts: 3748

General Information to Glycopyrrolate and Iontoporesis

Glycopyrrolate is a drug that as the aibility to suppress excessive sweating, the symptom of hyperidrosis.
Glycopyrrolate normally it is taken orally administered.
Glycopyrrolate can be brought into the body with iontophoresis, this is called medical iontophoresis too. Some do not get a really satisfying results with ionto, before taking the operation or ETS option, maybe it is worth to give Iontoporesis in conjunction wit Glycopyrrolate a trial. This special iontophoresis purpose is (different from tap water iontoporesis) indicated, allocated, controlled and prescribed by your dermatologist or doctor.

The good news is that Glycopyrrolate can be dissolved in water and brought into the skin via Iontoporesis. T More good news is, that possible side effects of the drug Glycopyrrolate in conjunction with Iontoporesis to treat excessive sweating, are in many cases not so serious (or milder, if any) than when taking it orally.
Why this? Easy thing: the Glycopyrrolate (when you do it the way it supposed to be) is brought in contact with the upper skin area only, and is because of this the glycopyrrolate is not spread over the wole body.
To reach the same % of the concentration in the upper skin, when taken it orally is much higher.
E.g.: When you only want to treat a area of 100 cm2 that weights only 50 gramms it does not really make sense to take it orally for a body weight of 80 kg, the math factor is 1: 4000
- if the side effects of the drug is suppressed by the same factor, you would have the 4000th part of the side effect when taken it orally.

Please keep in mind: We are not doctors, so these statements are only mathematic and cannot be really assigned into medical reality, for concrete medical information you should always ask your doctor

However Glycopyrrolate with Iontoporesis users can have the same (hopefully not in the same proportion) side effects, when taken orally.

In fact - if it works - it does not only reduce excesive sweat, it has also contraindications that can be:

So far, now to the request:
First, why do they alter the polarity? this does not make any sense when the hand is still in the tray.

In order to prevent systemic effects, a good support should keep an eye open when systemic side effects occur. This can be a sign that the drug is being brought too deeply into the body, so the factors:

current strength
drug concentration
treatment length

should be readjusted to the personal needs of the patient , the best is indeed when the balance between these factors allow the best possibility for a treatment without (or as less as possible) side effects and a total sweat free effect.
To begin, it is a good idea to set the mA in direct current mode to 2-5 mA or 4-10 volts, the time to 5 minutes (this is enough to get the glycon in the hands) and the concentration to 1 mg per litre.

The prefect water height should be chosen according to the heighth that the sweat goes to, if it is partial the areas that should not get the glyco can be covered before treatment with a good skin care ( www.current-care.info )

Now it is important if the glyco is poled (on the med is there a + or - or neutral for iontophoresis)
If it is not, as far as I know the normal glyco is neutraland
you can place the glyco in both trays.

A polarity switch only makes sense if the glyco is a poled one, the polarity change makes sense to make sure that the glyco will go into the skin.

If you do it in both trays

There is a correspondance in how much you put in the trays (in mg) in how much water (in ml) with how much current (in mA) and the time (in minutes) .
This factor describes how much will go how deep into the skin.

The depth is more like the factor of time and current strength.
The "how much" is more like the factor of glyco in how much water.
Iontophoresis pushes any med or even homeopathic solutions deep into the skin, the longer you do it the more will "walk" into the body (and blood circulation).

You can e.g. drive voltaren deep into a joint by placing the voltaren gel at one side of the joint, then laying one pole over the area you've ve placed the voltaren - the other at the opposite side of the joint. If you treat too short the voltaren will be before the "inner" joint, if you treat right it will be in the joint and if you treat too long it will be in the skin under the other electrode.

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